Tobacco Dust Exposure Among Tobacco Workers in Jember Reduces Lung Function Capacity
DOI:
https://doi.org/10.47134/ijhis.v3i2.60Keywords:
cotinine, tobacco dust exposure, lungs capacity, obstructive lungs disease, restictive lungs diseaseAbstract
This study investigated the association between urinary cotinine levels and lung function among tobacco workers in Jember Regency, a major tobacco-producing region in Indonesia. A total of 48 respondents were included based on specific inclusion and exclusion criteria. Urinary cotinine levels were measured using enzyme-linked immunosorbent assay (ELISA), and lung function was assessed via spirometry. Based on FEV1/FVC ratios, 58% of participants exhibited restrictive lung patterns, 29% showed obstructive patterns, and 13% had normal pulmonary function. Statistical analysis conducted using SPSS, with a significance level set at p < 0.05, indicated no statistically significant correlation between urinary cotinine levels and lung function.
References
1. Alegantina, S. (2017). Penetapan Kadar Nikotin dan Karakteristik Ekstrak Daun Tembakau ( Nicotiana tabacum L .) Determination of Nicotine Levels in Tobacco Leaves and Characteristics of Tobacco Leaves Extract ( Nicotiana tabacum L .). Jurnal Penelitian Dan Pengembangan Pelayanan Kesehatan, 1(2), 113–119.
2. Aziz, A. M., Srisurani W. A., I., & Tursina, M. Q. (2020). Perbedaan Forced Vital Capacity (FVC) pada Wanita Menopause dan Wanita Usia Subur Pekerja Pabrik Tembakau. Jurnal Kesehatan, 8(1), 63–70. https://doi.org/10.25047/j-kes.v8i1.145
3. Dominelli, P. B., & Molgat-Seon, Y. (2022). Sex, gender and the pulmonary physiology of exercise. European Respiratory Review, 31(163). https://doi.org/10.1183/16000617.0074-2021
4. Indriani, A., Wijayanti, I., & Awalia, H. (2023). Peran Perempuan dalam Usaha Tani Tembakau di Desa Sakra Selatan. Proceeding Seminar Nasional Mahasiswa Sosiologi, 1(1), 373–386.
5. Kumboyono, K., Chomsy, I. N., Hidayat, W. S., Hakim, A. K., Shalshabilla, N. N., Sujuti, H., Tjahtjono, C. T., Srihardyastutie, A., Hariyanti, T., & Wihastuti, T. A. (2023). Factors Affecting the Serum Cotinine Level of Male SmokersinMalang,Indonesia. International Journal of Medical Toxicology and Forensic Medicine, 13(3), E40130. https://doi.org/10.32598/ijmtfm.v13i3.40130
6. Maulidiyah, A. A., & Darsono, D. (2024). Analisis Faktor-Faktor Yang Memengaruhi Ekspor Tembakau Di Kabupaten Jember. Agricultural Socio-Economic Empowerment and Agribusiness Journal, 2(2), 68. https://doi.org/10.20961/agrisema.v2i2.74829
7. Maulidiyah, A. A., & Darsono, D. (2024). Analisis Faktor-Faktor Yang Memengaruhi Ekspor Tembakau Di Kabupaten Jember. Agricultural Socio-Economic Empowerment and Agribusiness Journal, 2(2), 68. https://doi.org/10.20961/agrisema.v2i2.74829
8. Tanner, J. A., Prasad, B., Claw, K. G., Stapleton, P., Chaudhry, A., Schuetz, E. G., Thummel, K. E., & Tyndale, R. F. (2017). Predictors of variation in CYP2A6 mRNA, protein, and enzyme activity in a human liver bank: Influence of genetic and nongenetic factors. Journal of Pharmacology and Experimental Therapeutics, 360(1), 129–139. https://doi.org/10.1124/jpet.116.237594
9. Wang, J., Xue, T., Ye, H., Sang, C., Wu, S., & Li, S. (2021). Study of the common activating mechanism of apoptosis and epithelial-to-mesenchymal transition in alveolar type II epithelial cells. Respiratory Physiology and Neurobiology, 284(October 2020), 103584. https://doi.org/10.1016/j.resp.2020.103584
10. Zagà, V., Dell’Omo, M., Murgia, N., & Mura, M. (2021). Tobacco Worker’s Lung: A Neglected Subtype of Hypersensitivity Pneumonitis. Lung, 199(1), 13–19. https://doi.org/10.1007/s00408-020-00416-4
11. Zysman, M., & Raherison-Semjen, C. (2022). Women’s COPD. Frontiers in Medicine, 8(January), 13–16. https://doi.org/10.3389/fmed.2021.600107
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